Human erythrocyte membrane enzymes: current status and clinical correlates
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منابع مشابه
Human erythrocyte membrane enzymes: current status and clinical correlates.
By Stanley L. Schrier T HE PAST TWENTY YEARS have seen a remarkable growth in information concerning the metabolism of the human erythrocyte. It became apparent that, depending on the method of preparation, some of the enzymes of the human erythrocyte can be recovered partially or totally in an operationally defined membrane fraction. Therefore, there now exists a substantial body of informatio...
متن کاملEnzymes of the Human Erythrocyte
The enzymatic interconversion involves a net transfer of hydrogen which migrates as a proton (1). In spite of an early reference (2) to the role and existence of this glycolytic enzyme within a variety of animal tissues, it apparently has not been prepared previously in a significantly purified state from any source. Fractions rich in this enzyme have been separated from rabbit muscle (3), and ...
متن کاملEnzymes of the Human Erythrocyte
A detailed description of appropriate procedures for the isolation in presumably ahnost pure form of a purine nucleoside phosphorylase from human erythrocytes was presented as the original report of Paper I (1). The present paper will s ummarize the results of investigations concerning the stability characteristics and kinetic properties of the isolated enzyme. Enzymatic degradation of nucleosi...
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Fraker, P. J. & Speck, J. C., Jr. (1978) Biochem. Biophys. Res. Snary, D., Goodfellow, P., Hayman, M. J., Bodmer, W. F. & Commun. 80,849-857 Hubbard, A. L. & Cohn, 2. A. (1976) in Biochemical Analysis of Okayama, H., Ueda, K. & Hayaishi, 0. (1978) Proc. Natl. Acad. Sci. Membranes (Maddy, A. H., ed.), pp. 427-501, Chapman and Hall, London Zittle, C. A. (1951) Adv. Enzymol. Relat. Areas Mol. Biol...
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Erythrocytes and their isolated membranes display ATP-dependent endocytosis. To localize the enzymes responsible for this phenomenon, the erythrocyte membranes (ghosts) were fractionated under conditions which retained ATPase activity. Fractionation of the ghosts resulted in three fractions: spectrin-actin, the peripheral proteins soluble in high salt, and the smooth membrane containing integra...
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ژورنال
عنوان ژورنال: Blood
سال: 1977
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v50.2.227.227